When implemented into clinical practice, this research is expected that a viable pharmacological option for promoting neuroprotection and maximizing offer functional recovery after traumatic spinal cord injury.
Results will be published shortly demonstrate that systemic administration of ALC soon after a paralyzing injury promoted the milestone recovery of walking ability. In contrast to the control group given no ALC, the only slight hind leg movements. Again, the group treated with ALC recovered hindlimb movements more quickly and were able to stand on all four limbs and go a month later Crucially, such a remarkable recovery with significant tissue sparing at the injury site was correlated to the administration of ALC.‘Hairpin Peptidomimetics That is a promising new class of drug,’says Robinson. ‘We hope that will make it possible in developing a drug for HIV treatment on that basis. ‘.
They made with a peptide a molecule which mimics the structure of the desired peptide. The group has already shown to A – by helical peptides be imitated with a so-called A – hairpin. The researchers attached side chains of robust framework of the hair pin , so that the groups of atoms needed in molecular recognition to be presented, Robinson, as they the original original helical peptide.
Angewandte Chemie International International Edition, doi: 10.1002/anie.