We look back on some of the important insights into biomedicine published this year.

In recent years, the drug provides been reintroduced under rigid control for different indications, such as for example cancer. Yet despite almost half of a century of research, most of the molecular targets underlying the developmental defects caused by thalidomide stay unclear. This March, Japanese scientists identified a protein known as cereblon to which thalidomide binds. Today, thalidomide is used clinically to treat individuals with multiple myeloma and leprosy, so understanding the molecular targets of thalidomide and their roles in limb formation can help make safer derivatives of the drug.These eggs, in theory, will produce chickens that continue to lay hypoallergenic eggs then. The genes and DNA of the poultry remain unaltered. There’s also potential for the research to lead to allergy-free flu vaccines, some of which contain traces of egg. Previous projects, such as one executed by Swiss and German chemists in 2008, have appeared at ways in which regular eggs could possibly be treated in order to make them secure for intake by allergy-sufferers. Others possess cloned the allergen genes, but this task is reportedly the first one that is wanting to render the proteins harmless.

Deirdre K.