Damaged RNAs were often in the brains of aging animals and patients with neurodegenerative diseases, as Alzheimer’s disease and demonstrated Parkinson’s disease fler recensioner här . However, because the cellular pathways for recognizing and degrading these RNAs is unknown, it was not possible determine whether RNA damage contributes to to aging or age-related diseases. A doctorate is Wolin the identification of genes in detecting and degrading damaged RNAs involved and determine whether they contribute senescence. identified identified these important genes in yeast, we will decide whether the same components are involved in this process in mouse and human cells, said Wolin. We will also determine whether the failure degrade damaged RNAs contributes to senescence in mouse and human cells. Knowing how RNA damage or aging could contribute to neurodegeneration broader significance for the design of drugs with the potential to. .
At Yale are named Frank J. Associate professor of molecular, cell and developmental biology, and Sandra L. Professor of Cell Biology and Molecular Biophysics & Biochemistry.
Work with rats, developing by Dr. Lam and colleagues conducted a series of elegant experiments which shown first time that lipids or fats which type the small intestines triggering you afferent neural signal to the brain that sends signals at which liver glucose production and the bottom blood glucose levels at less than 15 min. No drop in the levels have taken place if nerve been reduced or blocks between the gut and brain or between your brain and the liver. The shutter release button on lower glucose were also canceled when rats fat diets for three days prior to experimentation an statement which suggests that those who eat a high fat diet is lose this beneficial pathway were fed.