However, we record a listing of the annual number of bleeding episodes and aspect IX use over a longer follow-up period for the six sufferers in the initial dose-escalation cohort. Results Individuals Of the 10 individuals with severe hemophilia B who were enrolled in the study, all had negative test results for human immunodeficiency virus . All the patients except Patient 7 had proof serologic immunity to hepatitis B surface area antigen after vaccination. All the patients except Individuals 1, 4, and 6 had evidence of previous illness with hepatitis C virus , based on tests that was positive for HCV antibodies but detrimental for HCV RNA.Medication and Food Administration for the prevention of AF. AF is considered an epidemic coronary disease. The estimated number of individuals with AF globally in 2010 2010 was 33.5 million. Based on the 2014 American Center Association report on CARDIOVASCULAR DISEASE and Stroke Statistics, the estimated number of individuals with AF in the U.S. In 2010 2010 ranged from 2.7 to 6.1 million. AF increases the risk of stroke and could donate to worsening heart failure also. This is a significant milestone for the company and for the advancement of Gencaro, stated Dr.